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In this paradigm-shifting book from acclaimed Harvard Medical School doctor and one of TIME magazine's 100 most influential people on earth, Dr. David Sinclair reveals that everything we think we know about ageing is wrong, and shares the surprising, scientifically-proven methods that can help readers live younger, longer.

For decades, the medical community has looked to a variety of reasons for why we age, and the consensus is that no one dies of old age; they die of age-related diseases. That's because ageing is not a disease - it is inevitable.

But what if everything you think you know about ageing is wrong?

What if ageing is a disease? And that disease is curable.

In Lifespan, Dr David A. Sinclair, one of the world's foremost authorities on genetics and ageing, argues just that. He has dedicated his life's work to chasing more than a longer lifespan - he wants to enable people to live longer, healthier, and disease-free well into our hundreds. In this book, he reveals a bold new theory of ageing, one that pinpoints a root cause of ageing that lies in an ancient genetic survival circuit. This genetic trick - a circuit designed to halt reproduction in order to repair damage to the genome - has enabled earth's early microcosms to survive and evolve into more advanced organisms. But this same survival circuit is the reason we age: as genetic damage accumulates over our lifespans from UV rays, environmental toxins, and unhealthy diets, our genome is overwhelmed, causing gray hair, wrinkles, achy joints, heart issues, dementia, and, ultimately, death.

But genes aren't our destiny; we have more control over them than we've been taught to believe. We can't change our DNA, but we can harness the power of the epigenome to realise the true potential of our genes. Drawing on his cutting-edge findings at the forefront of medical research, Dr Sinclair will provide a scientifically proven roadmap to reverse the genetic clock by activating our vitality genes, so we can live younger for longer. Readers will discover how a few simple lifestyle changes - like intermittent fasting, avoiding too much animal protein, limiting sugar, avoiding x-rays, exercising with the right intensity, and even trying cold therapy - can activate our vitality genes. Dr Sinclair ends the book with a look to the near future, exploring what the world might look like - and what will need to change - when we are all living well to 120 or more.

Dr Sinclair takes what we have long accepted as the limits of human potential and mortality and turns them into choices.

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A spectacularly illustrated history of an enigmatic surgical diagram

The Wound Man--a medical diagram depicting a figure fantastically pierced by weapons and ravaged by injuries and diseases--was reproduced widely across the medieval and early modern globe. In this panoramic book, Jack Hartnell charts the emergence and endurance of this striking image, used as a visual guide to the treatment of many ailments. Taking readers on a remarkable journey from medieval Europe to eighteenth-century Japan, Hartnell explains the historic popularity of this gruesome image and why the Wound Man continues to intrigue us today.

Drawing on a wealth of original research, Hartnell traces the many lives of the Wound Man, from its origins in late medieval Bohemia to its vivid reincarnations in hundreds of manuscripts and printed books over more than three hundred years. Transporting readers beyond the specifics of bodily injury, Hartnell demonstrates how the Wound Man's body was at once an encyclopedic repository of surgical knowledge, a fantastic literary and religious muse, a catalyst for shifting media landscapes, and a cross-cultural artistic feat that reached diverse audiences around the world. The Wound Man, we discover, held profound importance not only for healers and patients but also for scribes, students, nuns, monks, printmakers, and poets.

Marvelously illustrated, Wound Man sheds light on the entwined histories of art and medicine, showing how premodern medical diagrams represent a unique site of contact between sickness, cure, painting, and print.

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The Checklist Manifesto

How to Get Things Right

by Atul Gawande