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Sinclair",{"_810":826,"_812":837,"_783":1009},"

In this paradigm-shifting book from acclaimed Harvard Medical School doctor and one of TIME magazine's 100 most influential people on earth, Dr. David Sinclair reveals that everything we think we know about ageing is wrong, and shares the surprising, scientifically-proven methods that can help readers live younger, longer.

For decades, the medical community has looked to a variety of reasons for why we age, and the consensus is that no one dies of old age; they die of age-related diseases. That's because ageing is not a disease - it is inevitable.

But what if everything you think you know about ageing is wrong?

What if ageing is a disease? And that disease is curable.

In Lifespan, Dr David A. Sinclair, one of the world's foremost authorities on genetics and ageing, argues just that. He has dedicated his life's work to chasing more than a longer lifespan - he wants to enable people to live longer, healthier, and disease-free well into our hundreds. In this book, he reveals a bold new theory of ageing, one that pinpoints a root cause of ageing that lies in an ancient genetic survival circuit. This genetic trick - a circuit designed to halt reproduction in order to repair damage to the genome - has enabled earth's early microcosms to survive and evolve into more advanced organisms. But this same survival circuit is the reason we age: as genetic damage accumulates over our lifespans from UV rays, environmental toxins, and unhealthy diets, our genome is overwhelmed, causing gray hair, wrinkles, achy joints, heart issues, dementia, and, ultimately, death.

But genes aren't our destiny; we have more control over them than we've been taught to believe. We can't change our DNA, but we can harness the power of the epigenome to realise the true potential of our genes. Drawing on his cutting-edge findings at the forefront of medical research, Dr Sinclair will provide a scientifically proven roadmap to reverse the genetic clock by activating our vitality genes, so we can live younger for longer. Readers will discover how a few simple lifestyle changes - like intermittent fasting, avoiding too much animal protein, limiting sugar, avoiding x-rays, exercising with the right intensity, and even trying cold therapy - can activate our vitality genes. Dr Sinclair ends the book with a look to the near future, exploring what the world might look like - and what will need to change - when we are all living well to 120 or more.

Dr Sinclair takes what we have long accepted as the limits of human potential and mortality and turns them into choices.

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Almost one in three Australians struggle with obesity and its related health conditions, including high blood pressure, heart disease and diabetes. It is a health care crisis that affects life expectancy and quality of life, and yet for decades medical bias and societal pressure has left many feeling judged, confused and often left behind.

Now New York Times bestselling author and former US Food and Drug Administration commissioner Dr David A. Kessler urges us to see obesity in a new light. In Diet, Drugs, and Dopamine, he shares new evidence that obesity is not only a phenomenon of the body, but one that starts in the brain.

In this groundbreaking book, Kessler--a lifelong public health advocate--explains how processed food has changed our brain chemistry, creating both an addiction to highly rewarding foods and compulsive cravings that cause us to eat more. But this change doesn't have to be permanent. Illuminating cutting-edge research on the many factors that influence weight--from neuroscience to nutrition--Diet, Drugs, and Dopamineexplains why maintaining weight loss is almost insurmountably difficult and what we can learn from addiction science and eating-disorder-recovery protocols to forge a new way forward.

Kessler offers a clear-eyed view of the recent, much-publicised pharmaceuticals promoted as a solution to obesity and a critical examination of this new class of drugs. While these drugs will offer a panacea to some, they also carry serious and potentially long-term risks that must be seriously investigated before we regard them as a sustainable option.

Eye-opening, provocative, and empowering, this book is a must-read for anyone who has ever struggled to maintain their body weight--which is to say, everyone.

David A. Kessler, M.D., served as commissioner of the US Food and Drug Administration under presidents George H. W. Bush and Bill Clinton. He is a paediatrician and has been the dean of the medical schools at Yale and the University of California. He is the father of two and lives with his wife in Washington, DC.

'A great read! Really excellent stuff. Kessler brilliantly walks the tightrope between the hype and the criticism around the new weight loss drugs--weaving personal stories with superbly accessible science. An important and illuminating book.' Chris van Tulleken, author of Ultra-Processed People

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The Menopause Brain

The New Science for Women to Navigate Midlife, and Optimise Brain Health for Later Years

by Lisa Mosconi

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