A year after the devastating events that took place in Fool Me Once, a secret from former Detective Sami Kierce's college days comes back to haunt him. Present day is hard enough for Kierce, but his past isn't through with him yet...

Sami Kierce, a young college grad backpacking in Spain with friends, wakes up one morning, covered in blood. There's a knife in his hand. Beside him, the body of his girlfriend. Anna. Dead. He begins to scream - and then he runs.

Twenty two years later, Kierce, now a private investigator, is a new father who's working off his debts by teaching wannabe sleuths at a night school in New York City. One evening, he recognizes a familiar face at the back of the classroom. Anna. It's unmistakably her. But as soon as he makes eye contact with her, she bolts.